About a year ago my nine year old Weimaraner developed a limp and pain which was coming from the spine. After medication from the doctor and very restricted activity, she continued to limp. The doctor recommended MSM, but the clerk at the health food store said she heard good reviews about ActiPet, Hip & Joint Defense for Dogs. I have been giving ActiPet to my dog over a year, and now at ten years old, she is back to running, jumping, and does not appear to be in any pain. We are amazed at the results. ActiPet has given an old dog quality of life again.