I bought this product at the recommendation of a Facebook friend. My husband had 'done something' to his shoulder tossing a 5-gallon bucket lid like a frisbee (we live on a farm). He iced and used a sling to immobilize the shoulder, but it didn't improve even after 4 days. With the first application, on day 5, he noticed immediate improvement. He continued to use the DMSO morning and evening for three more days and his arm was back to normal. He used it a few more times and has had no additional trouble with his shoulder (though he has decided to retire from anything resembling frisbee!).
My daughter has autoimmune pain isses. We are trying this with her some, but not seeing the great improvement we saw with my husband's shoulder.
I will be keeping DMSO on hand for the aches and pains that come from working and playing hard on the farm!