Primal Defense is a very good product that is a godsend, since all other "probiotics" rarely work as they claim they will. I believe it is Primal's special blend that gives it an advantage over others. I had been taking this product for about a year, nearly two years ago, then quit. I regretted doing that because I developed worsening symptoms very recently, such as new attacks of IBS (diarrhea mostly), burning, gassiness, etc. I am just starting to take it again tonight and I will tell you, I already feel the difference. It's not a "miracle pill", but it really works and, when taken consistently, can really help people with digestive problems. It's worth trying a bottle to see if it works for you!