Serrapeptase is great! I had no digestive issues like other people write in reviews or stomach cramps or other problems. Recently I found out that my cholesterol is high even though I walk at least 5 km a day and eat Mediterranean cuisine, use only olive oil, I don't fry any food at all, don't eat pork, eat a lot of greens, don't drink juices full of sugar or sodas, don't eat any food that is not fresh prepared. I was feeling tired all day, sometimes my joints would hurt and be swollen, I couldn't get out of bed even though I slept more then 8 hours. I started to explore the internet hoping to find answers and run into this enzyme. I was skeptic at first because they call it miracle enzyme but decided to try it out. With one tablet a day I stopped feeling off all the time. My life changed. Today that I forgot to order Serrapeptase and I am without tablets for 3rd day in a row, I can feel what this enzymes is doing for me. After 3 days without I am tired, my joints swollen and I feel dull.