I have had Chronic Lyme disease, cfs, fibromyalgia, Babesoisis, and other related health issues for the last four years. DMSO Liquid Glass 99.9 Pure helped me to regain mobility in my back and my spine. For over two years, I had the feeling of being struck by a 2x4 24/7. Like white noise from a TV, I became accustomed to the pain although energy was pretty much nil. I was sent 99% Pure DMSO from a kindly member on a chronic disease board telling me it had helped them immensely. How it is to be used: clean applicator EACH time never double dip into the jar to prevent contamination. Paint a thin layer over the painful area TOPICALLY and let dry. Repeat about 1-2 daily. That was how I did it at least. It took a week, but such a relief to have that sensation gone and not have my strength zapped like that. ALWAYS make sure DMSO is 99% pure, in a glass bottle and NOT a 70/30 solution.