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Sumatriptan

Brand Name: Imitrex®

Sumatriptan Information

is a member of the selective serotonin receptor agonist family of drugs used to treat, but not prevent, migraine headaches. is available in injection, nasal spray, and oral tablet forms.

Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)

Avoid Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results.

5-Hydroxytryptophan (5-HTP)*

L-tryptophan*

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Sumatriptan Interactions with Dietary Supplements

5-Hydroxytryptophan (5-HTP) and L-tryptophan
works by stimulating serotonin receptors in the brain. 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with sumatriptan could increase sumatriptan-induced side effects. However, no interactions have yet been reported with sumatriptan and 5-HTP or L-tryptophan.

Sumatriptan Interactions with Foods and Other Compounds

Food
tablets may begin to work faster when taken with fluid on an empty stomach at the first sign of migraine.1 2



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