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Repaglinide Information
is used to treat individuals with type 2 (non-insulin-dependent) diabetes mellitus; it is in the meglitinide class of
anti-diabetic drugs. It may be used as an adjunct to diet and exercise either alone or in
combination with other anti-diabetic medications.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results. |
Ginkgo biloba
Willow*
|
Check: Other—Before taking any of these supplements or eating any of
these foods with your medication, read this article in full for details. |
Vitamin B3
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Supportive interaction |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Repaglinide Interactions with Dietary Supplements
Vitamin B3
(niacin)
Supplementation with large amounts of niacin (also called nicotinic acid) can increase blood
glucose levels in diabetics, which might
interfere with the blood-sugar-lowering effects of repaglinide.1 The form of
vitamin B3 known as niacinamide does not have this effect. People who start or stop
supplementing niacin while on repaglinide should carefully monitor their blood sugar levels
and consult their prescribing doctor about making adjustments in the daily amount of drug
taken.
Repaglinide Interactions with Herbs
Willow
(Salix alba)
Willow bark contains salicin, which is related to
aspirin. Both salicin and aspirin produce anti-inflammatory effects after they have been
converted to salicylic acid in the body. Taking aspirin together with repaglinide enhances the
blood-sugar-lowering effects of the drug,2 which might result in unwanted side
effects. Controlled research is needed to determine whether taking willow bark together with
repaglinide might produce similar effects.
Ginkgo
biloba
In a preliminary trial, administration of Ginkgo biloba extract (120 mg per day) for
three months to patients with type 2 diabetes who were taking oral anti-diabetes medication
resulted in a significant worsening of glucose tolerance. Ginkgo did not impair glucose
tolerance in individuals whose diabetes was controlled by diet.3 Individuals taking
oral anti-diabetes medication should consult a doctor before taking Ginkgo
biloba.
Repaglinide Interactions with Foods and Other Compounds
Food
Taking repaglinide with food can result in decreased absorption of the drug.4
Consequently, to achieve the best results, repaglinide should be taken on an empty
stomach.
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Copyright © 2004 Healthnotes, Inc. All rights reserved.
www.healthnotes.com
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disclaimer about the limitations of the information provided here. Do NOT rely solely on
the information in this article.
Learn more about Healthnotes, the
company.
Learn more about the authors of Using Medicines
with Vitamins and Herbs
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. The "reviews" listed for any medical condition, prescription drug, condition or symtpom is provided specifically from eVitamins and is not associated with healthnotes.
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