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Ranitidine Information
is a member of the H-2 (histamine blocker) family of drugs, which prevents the
release of acid into the stomach. is used to treat stomach and duodenal ulcers, gastroesophageal reflux disease, erosive
esophagitis, and Zollinger-Ellison syndrome. is available as a prescription drug
and also as a nonprescription over-the-counter product for relief of heartburn.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
 May be Beneficial: Depletion or
interference—The medication may deplete or interfere with the absorption or
function of the nutrient. Taking these nutrients may help replenish them. |
Folic acid
Iron
Vitamin B12*
|
Avoid: Reduced drug absorption/bioavailability—Avoid these supplements
when taking this medication since the supplement may decrease the absorption and/or activity
of the medication in the body. |
Magnesium hydroxide
Tobacco
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| Side effect reduction/prevention |
None known
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| Supportive interaction |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Ranitidine Interactions with Dietary Supplements
Folic
acid
Folic acid is needed by the body to utilize
vitamin B12. Antacids, including ranitidine, inhibit folic acid absorption.1
People taking antacids are advised to supplement with folic acid.
Iron
Stomach acid may facilitate iron absorption. H-2 blocker drugs reduce stomach acid and are
associated with decreased dietary iron absorption.2 People with ulcers may also be
iron deficient due to blood loss and benefit from iron supplementation. Iron levels in the
blood can be checked with lab tests.
Magnesium
In healthy volunteers, a magnesium
hydroxide/aluminum hydroxide antacid,
taken with ranitidine, decreased ranitidine absorption by 20%–25%.3 It was
unclear from this study if magnesium or the specific form of magnesium as magnesium hydroxide
was part of the problem. It is not known if other forms of magnesium would cause this problem.
People can avoid this interaction by taking ranitidine two hours before or after any
aluminum/magnesium-containing antacids,
including magnesium hydroxide found in some
vitamin/mineral supplements.
Vitamin
B12
Stomach acid is needed to release vitamin B12 from food so it can be absorbed by the body. H-2
blocker drugs reduce stomach acid and are associated with decreased dietary vitamin B12
absorption.4 The vitamin B12 found in supplements is available to the body without
the need for stomach acid. Lab tests can determine vitamin B12 levels.
Ranitidine Interactions with Foods and Other Compounds
Food
may be taken with or without food.5
Tobacco (Nicotiana species)
A study of 18 healthy people found smoking decreased the acid blocking effects of
ranitidine.6
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Review Date: 8/5/2007
Medication: Ranitidine -  - Very Good
Medication Type: Generic
Length Taken: Less than 1 month
Strength: 75 mg. X 1 times per day
Side Effects: None
Other Products Taken:
Ranitidine works great and it is a lot cheaper than the brand name version (Zantac).
Anonymous
United States
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Review Date: 6/28/2008
Medication: Ranitidine -  - Below Average
Medication Type: Generic
Length Taken: Between 3 and 6 months
Strength: 150 mg X 2 times per day
Other Products Taken: Multivitamin, Multimineral
I was not aware of the need to supplement with this medication. I recently, had numbness in my feet, hands and face. I didn't have energy. It was also around my period and I didn't know why I felt so badly until I researched and found that Zantac depletes B vitamins and others. I went to the store and bought some B complex with B-12 having 1,200 mg. I feel perfect now. The product works, but I wish they would have told me to supplement. I went months with high anxiety that could have been avoided had the makers of this product gave a warning.
Anonymous
Columbus, OH USA
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Copyright © 2004 Healthnotes, Inc. All rights reserved.
www.healthnotes.com
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disclaimer about the limitations of the information provided here. Do NOT rely solely on
the information in this article.
Learn more about Healthnotes, the
company.
Learn more about the authors of Using Medicines
with Vitamins and Herbs
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. The "reviews" listed for any medical condition, prescription drug, condition or symtpom is provided specifically from eVitamins and is not associated with healthnotes.
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