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Lansoprazole Information
is a “proton pump inhibitor” drug that blocks production of
stomach acid. is used to treat diseases in which stomach acid causes damage,
including stomach and duodenal ulcers,
esophagitis, and Zollinger-Ellison syndrome.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
May be Beneficial: Depletion or
interference—The medication may deplete or interfere with the absorption or
function of the nutrient. Taking these nutrients may help replenish them. |
Beta-carotene*
Folic acid
Vitamin B12* (dietary, not supplemental B12)
|
May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Cranberry*
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| Side effect reduction/prevention |
None known
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| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Lansoprazole Interactions with Dietary Supplements
Beta-carotene
Omeprazole, a drug closely related to
lansoprazole, taken for seven days led to a near-total loss of stomach acid in healthy people
and interfered with the absorption of a single administration of 120 mg of
beta-carotene.1 It is unknown whether repeated administration of beta-carotene
would overcome this problem or if absorption of carotenoids from food would be impaired.
Persons taking omeprazole and related acid-blocking drugs for long periods may want to have
carotenoid blood levels checked, eat plenty of
fruits and vegetables, and consider
supplementing with carotenoids.
Folic
acid
Folic acid is needed by the body to utilize
vitamin B12. Antacids, including lansoprazole, inhibit folic acid absorption.2
People taking antacids are advised to supplement with folic acid.
Vitamin
B12
Omeprazole, a drug closely related to lansoprazole, has interfered with the absorption of
vitamin B12 from food (though not supplements) in some,3 4 but not all,
studies.5 6 This interaction has not yet been reported with
lansoprazole. However, a fall in vitamin B12 status may result from decreased stomach acid
caused by acid blocking drugs, including lansoprazole.7
Lansoprazole Interactions with Herbs
Cranberry (Vaccinium macrocarpon)
Omeprazole was shown to reduce protein-bound
vitamin B12 absorption and cranberry juice was
shown to increase protein-bound vitamin B12 absorption in eight people treated with omeprazole
(a drug closely related to lansoprazole).8 While this effect has not been studied
with lansoprazole, people taking lansoprazole may choose to drink cranberry juice or other
acidic liquids with vitamin B12-containing foods. Unlike vitamin B12 found in food, vitamin
B12 found in supplements is not bound to peptides (pieces of protein). The absorption of B12
supplements therefore does not require acid and is unlikely to be improved by drinking
cranberry juice.
Lansoprazole Interactions with Foods and Other Compounds
Food
The initial dose of lansoprazole should be taken 30 minutes before a meal.9
Subsequent doses are equally effective taken with or without food but should be taken at the
same time every day.10 Capsules and granule contents should not be chewed or
crushed. However, lansoprazole capsules may be opened, the granule contents sprinkled on one
tablespoon of applesauce, then immediately swallowed.
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Review Date: 6/19/2007
Medication: Lansoprazole - - Average
Medication Type: Generic
Length Taken: Between 6 and 12 months
Strength: 30 mg X 1 times per day
Side Effects: Stomach Pain, Constipation, Upset Stomach / Diarreha, Gave Me Gas or Made Me Bloated, Loss of Sex Drive, Weight Gain
Other Products Taken:
I have been using Lansoprazole for over a year. It seems that any time I use it, my stomach feels very hard and uncomfortable. Even though I get these feelings in my stomach, the medication does seem to help manage and get rid of my heartburn.
Mike
London, England
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Review Date: 4/7/2008
Medication: Lansoprazole - - I Love It
Medication Type: Generic
Length Taken: More than 1 year
Strength: 30 mg X 1 times per day
Side Effects: Nausea, Stomach Pain
Other Products Taken: no
After years of pain & other symptoms including ulcers, I tried various drugs and even a trip to a Homeopath, Lansoprazole has eliminated all the symptoms of reflux disease, even some I didnt know were related. The only problem is that I do a lot of sports and I find that since I've been taking it I get indigestion, bloating and nausea after a long run or bike ride. I dont know if its something to do with digestion, it's a minor one though and wouldn't stop me taking it.
Anonymous
UK
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Review Date: 7/22/2008
Medication: Lansoprazole - - Very Good
Medication Type: Generic
Length Taken: Between 6 and 12 months
Strength: 15mg X 1 times per day
Other Products Taken:
Very good to start with, but I am now getting uncomfortable with the side effects after being on it for a while.
Anonymous
UK
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Review Date: 10/6/2008
Medication: Lansoprazole - - Below Average
Medication Type: Generic
Length Taken: Between 3 and 6 months
Strength: 30 mg X 1 times per day
Side Effects: Dizziness, Nausea, Stomach Pain, Made Me Nauseous
Other Products Taken:
I was prescribed Lansoprazole for a suspected stomach ulcer. I nearly managed to finish the first 28 day course, but towards the end, I was feeling so awful (nausea, dizziness, flu-like symptoms) I had to stop. About a month later, the stomach pain was becoming unbearable, so I tried Lansoprazole again; it's great at killing the stomach pain, but the side-effects are so debilitating, I had to stop again after just a few days on the tablets.
Anonymous
UK
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The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
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prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
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