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Lansoprazole

Brand Name: Prevacid®

Lansoprazole Information

is a “proton pump inhibitor” drug that blocks production of stomach acid. is used to treat diseases in which stomach acid causes damage, including stomach and duodenal ulcers, esophagitis, and Zollinger-Ellison syndrome.

Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)

Beneficial May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them.

Beta-carotene*

Folic acid

Vitamin B12* (dietary, not supplemental B12)

Beneficial May be Beneficial: Supportive interaction—Taking these supplements may support or otherwise help your medication work better.

Cranberry*

Side effect reduction/prevention

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Lansoprazole Interactions with Dietary Supplements

Beta-carotene
Omeprazole, a drug closely related to lansoprazole, taken for seven days led to a near-total loss of stomach acid in healthy people and interfered with the absorption of a single administration of 120 mg of beta-carotene.1 It is unknown whether repeated administration of beta-carotene would overcome this problem or if absorption of carotenoids from food would be impaired. Persons taking omeprazole and related acid-blocking drugs for long periods may want to have carotenoid blood levels checked, eat plenty of fruits and vegetables, and consider supplementing with carotenoids.

Folic acid
Folic acid is needed by the body to utilize vitamin B12. Antacids, including lansoprazole, inhibit folic acid absorption.2 People taking antacids are advised to supplement with folic acid.

Vitamin B12
Omeprazole, a drug closely related to lansoprazole, has interfered with the absorption of vitamin B12 from food (though not supplements) in some,3 4 but not all, studies.5 6 This interaction has not yet been reported with lansoprazole. However, a fall in vitamin B12 status may result from decreased stomach acid caused by acid blocking drugs, including lansoprazole.7

Lansoprazole Interactions with Herbs

Cranberry (Vaccinium macrocarpon)
Omeprazole was shown to reduce protein-bound vitamin B12 absorption and cranberry juice was shown to increase protein-bound vitamin B12 absorption in eight people treated with omeprazole (a drug closely related to lansoprazole).8 While this effect has not been studied with lansoprazole, people taking lansoprazole may choose to drink cranberry juice or other acidic liquids with vitamin B12-containing foods. Unlike vitamin B12 found in food, vitamin B12 found in supplements is not bound to peptides (pieces of protein). The absorption of B12 supplements therefore does not require acid and is unlikely to be improved by drinking cranberry juice.

Lansoprazole Interactions with Foods and Other Compounds

Food
The initial dose of lansoprazole should be taken 30 minutes before a meal.9 Subsequent doses are equally effective taken with or without food but should be taken at the same time every day.10 Capsules and granule contents should not be chewed or crushed. However, lansoprazole capsules may be opened, the granule contents sprinkled on one tablespoon of applesauce, then immediately swallowed.



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Medication Reviews & Side Effects for Lansoprazole



  Write an online review of Lansoprazole
Review Date: 6/19/2007
Medication: Lansoprazole - - Average
Medication Type: Generic
Length Taken: Between 6 and 12 months
Strength: 30 mg X 1 times per day
Side Effects: Stomach Pain, Constipation, Upset Stomach / Diarreha, Gave Me Gas or Made Me Bloated, Loss of Sex Drive, Weight Gain
Other Products Taken:

I have been using Lansoprazole for over a year. It seems that any time I use it, my stomach feels very hard and uncomfortable. Even though I get these feelings in my stomach, the medication does seem to help manage and get rid of my heartburn.

Mike
London, England

Review Date: 4/7/2008
Medication: Lansoprazole - - I Love It
Medication Type: Generic
Length Taken: More than 1 year
Strength: 30 mg X 1 times per day
Side Effects: Nausea, Stomach Pain
Other Products Taken: no

After years of pain & other symptoms including ulcers, I tried various drugs and even a trip to a Homeopath, Lansoprazole has eliminated all the symptoms of reflux disease, even some I didnt know were related. The only problem is that I do a lot of sports and I find that since I've been taking it I get indigestion, bloating and nausea after a long run or bike ride. I dont know if its something to do with digestion, it's a minor one though and wouldn't stop me taking it.

Anonymous
UK

Review Date: 7/22/2008
Medication: Lansoprazole - - Very Good
Medication Type: Generic
Length Taken: Between 6 and 12 months
Strength: 15mg X 1 times per day
Other Products Taken:

Very good to start with, but I am now getting uncomfortable with the side effects after being on it for a while.

Anonymous
UK

Review Date: 10/6/2008
Medication: Lansoprazole - - Below Average
Medication Type: Generic
Length Taken: Between 3 and 6 months
Strength: 30 mg X 1 times per day
Side Effects: Dizziness, Nausea, Stomach Pain, Made Me Nauseous
Other Products Taken:

I was prescribed Lansoprazole for a suspected stomach ulcer. I nearly managed to finish the first 28 day course, but towards the end, I was feeling so awful (nausea, dizziness, flu-like symptoms) I had to stop. About a month later, the stomach pain was becoming unbearable, so I tried Lansoprazole again; it's great at killing the stomach pain, but the side-effects are so debilitating, I had to stop again after just a few days on the tablets.

Anonymous
UK


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