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Glipizide Information
is a sulfonylurea drug used to lower blood sugar levels in people with type 2
(non-insulin-dependent) diabetes.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results. |
Fenugreek*
Ginkgo biloba
Gymnema sylvestre*
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Check: Other—Before taking any of these supplements or eating any of
these foods with your medication, read this article in full for details. |
Magnesium
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| Depletion or interference |
None known
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| Side effect reduction/prevention |
None known
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| Supportive interaction |
None known
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| Reduced drug
absorption/bioavailability |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Glipizide Interactions with Dietary Supplements
Magnesium
In a study of people with poorly controlled type 2 diabetes and low blood levels of magnesium,
treatment with glipizide was associated with a significant rise in magnesium
levels.1 In a randomized trial with eight healthy people, 850 mg magnesium hydroxide increased glipizide absorption and
activity.2 In theory, such changes could be therapeutic or detrimental under
varying circumstances. Therefore, people taking glipizide should consult with their doctor
before taking magnesium supplements.
Glipizide Interactions with Herbs
Fenugreek (Trigonella foenum-graecum)
In a randomized study of 15 patients with type 1 (insulin-dependent) diabetes, fenugreek (100 grams per day for ten days)
was reported to reduce blood sugar, urinary sugar excretion, serum cholesterol, and
triglycerides, with no change in insulin levels, compared with ten days of
placebo.3 In a study of 60 people with type 2 diabetes, fenugreek (25 grams per day
for 24 weeks) was reported to significantly reduce blood glucose levels.4 People
using glipizide should talk with their doctor before making any therapy changes.
Ginkgo
biloba
In a preliminary trial, administration of Ginkgo biloba who were taking oral
anti-diabetes medication resulted in a significant worsening of glucose tolerance. Ginkgo did
not impair glucose tolerance in individuals whose diabetes was controlled by diet.5
Individuals taking oral anti-diabetes medication should consult a doctor before taking
Ginkgo biloba.
Gymnema
sylvestre
Herbs such as Gymnema sylvestre will often improve blood-sugar control in
diabetics.
Glipizide Interactions with Foods and Other Compounds
Food
works best when taken 30 minutes before meals.6 Effective treatment of
type 2 diabetes with glipizide includes adherence to recommended dietary guidelines.
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Review Date: 3/21/2008
Medication: Glipizide -  - Below Average
Medication Type: Generic
Length Taken: More than 1 year
Strength: 5 X 2 times per day
Side Effects: Dry Mouth, Constipation, High Blood Pressure, Loss of Energy
Other Products Taken: Glucophage and quinapril Vitamins and minerals
Glipizide doesn't react fast enough on food and is really slow in controlling the sugar level.
Anonymous
New Mexico, USA
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www.healthnotes.com
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Learn more about the authors of Using Medicines
with Vitamins and Herbs
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. The "reviews" listed for any medical condition, prescription drug, condition or symtpom is provided specifically from eVitamins and is not associated with healthnotes.
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