Brand Name: Atridox®, Doryx®, Doxy®,
Monodox®, Periostat®, Vibramycin®
Doxycycline Information
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
 May be Beneficial: Depletion or
interference—The medication may deplete or interfere with the absorption or
function of the nutrient. Taking these nutrients may help replenish them. |
Vitamin K*
|
| May be Beneficial: Side effect
reduction/prevention—Taking these supplements may help reduce the likelihood and/or
severity of a potential side effect caused by the medication. |
Bifidobacterium longum*
Lactobacillus acidophilus*
Lactobacillus casei*
Probiotics*
Saccharomyces boulardii*
Saccharomyces cerevisiae*
Vitamin K*
|
| May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Saccharomyces boulardii*
|
Avoid: Reduced drug absorption/bioavailability—Avoid these supplements
when taking this medication since the supplement may decrease the absorption and/or activity
of the medication in the body. |
Minerals* (calcium, iron, magnesium, zinc)
|
|
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results. |
Milk or other dairy products
|
Check: Other—Before taking any of these supplements or eating any of
these foods
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Doxycycline Interactions with Dietary Supplements
Berberine-containing herbs
Berberine is a chemical extracted from
goldenseal (Hydrastis canadensis),barberry (Berberis vulgaris), and Oregon grape (Berberis aquifolium),
which has antibacterial activity. However, one double-blind study found that 100 mg berberine
given with tetracycline (a drug closely
related to doxycycline) reduced the efficacy of tetracycline in people with
cholera.1 In that trial, berberine may have decreased tetracycline absorption.
Another double-blind trial found that berberine neither improved nor interfered with
tetracycline effectiveness in cholera patients.2 Therefore, it remains unclear
whether a significant interaction between berberine-containing herbs and doxycycline and
related drugs exists.
Minerals
Many minerals can decrease the absorption and reduce effectiveness of doxycycline, including
calcium, magnesium, iron,
zinc, and others.3 To avoid these interactions, doxycycline should be taken two
hours before or two hours after dairy products
(high in calcium) and mineral-containing
antacids or supplements.
Probiotics
A common side effect of antibiotics is
diarrhea, which may be caused by the elimination of beneficial bacteria normally found in
the colon. Controlled studies have shown that taking probiotic microorganisms—such as
Lactobacillus casei, Lactobacillus acidophilus, Bifidobacterium
longum, or Saccharomyces boulardii—helps prevent antibiotic-induced
diarrhea.4
The diarrhea experienced by some people who take antibiotics also might be due to an
overgrowth of the bacterium Clostridium difficile, which causes a disease known as
pseudomembranous colitis. Controlled studies have shown that supplementation with harmless
yeast—such as Saccharomyces boulardii5 or Saccharomyces
cerevisiae (baker’s or brewer’s yeast)6 —helps prevent
recurrence of this infection. In one study, taking 500 mg of Saccharomyces boulardii
twice daily enhanced the effectiveness of the antibiotic vancomycin in preventing recurrent
clostridium infection.7 Therefore, people taking antibiotics who later develop
diarrhea might benefit from supplementing with saccharomyces organisms.
Treatment with antibiotics also commonly leads to an overgrowth of yeast (Candida
albicans) in the vagina (candida
vaginitis) and the intestines (sometimes referred to as “dysbiosis”).
Controlled studies have shown that Lactobacillus acidophilus might prevent candida
vaginitis.8
Vitamin
K
Several cases of excessive bleeding have been reported in people who take
antibiotics.9 10 11 12 This side effect may be the
result of reduced vitamin K activity and/or reduced vitamin K production by bacteria in the
colon. One
Doxycycline Interactions with Foods and Other Compounds
Food
may be taken with or without food and should be taken with a full glass of
water.14 However, doxycycline should not be taken with milk15 or other
dairy products.
|
|
Review Date: 7/25/2008
Medication: Doryx -  - Stay Far Away
Medication Type: Brand Name
Length Taken: More than 1 month but less than 3 months
Strength: 100 mg X 2 times per day
Side Effects: Depression, Mood Swings, Loss of Appetite, Loss of Energy, Increased Irritability
Other Products Taken:
This drug is the worst thing I have ever taken. I think it should be banned! It left me with excessive fatigue, depression and worst of all, a chronic sore tongue and burning mouth. It has dramatically altered my life, and not in a good way. If only I could turn the clock back and never have taken it.
Robin Kanstul
Arizona, USA
|
|
Review Date: 12/2/2008
Medication: Doxycycline -  - Very Good
Medication Type: Generic
Length Taken: Less than 1 month
Strength: 100 mg. X 3 times per day
Side Effects: Headache, Nausea, Stomach Pain, Loss of Appetite
Other Products Taken: Nexium and celexa
I am taking this for Lymes Disease and dramatically seen positive changes. However, I couldn't figure out why I still had a chronic headache until I stopped taking my vitamins. Apparently, it was the combination of supplements along with the doxy that did it for me. I was taking supplements long before the doxy. But when I introduced the doxy into my system, I couldn't shake my headaches. You MUST take it with food too. I get super queezy otherwise. I also make sure I take probiotics in between doses as well as eating yogurt.
Anonymous
Philadelphia, PA USA
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Learn more about the authors of Using Medicines
with Vitamins and Herbs
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. The "reviews" listed for any medical condition, prescription drug, condition or symtpom is provided specifically from eVitamins and is not associated with healthnotes.
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