Related Items: Anorexia nervosa, Binge Eating, Bulimia
Nervosa
Eating Disorders Information
Eating disorders are complex conditions involving psychological factors and nutritional
deficiencies. The term eating disorders includes anorexia nervosa, bulimia, and
binge-eating.
The psychological factors may include an inability to cope with stress, problems with
family and other relationships, feelings of deprivation, and experiences of physical, sexual,
or emotional abuse. Psychotherapy is an essential part of the treatment for eating disorders,
along with nutrition counseling and medical care as needed.1
A person with anorexia does not eat enough to maintain a healthy weight; she views herself
as overweight and is anxious about gaining weight. Anorexia typically begins in early
adolescence, mainly among girls, though the numbers of boys developing this condition is
increasing. People with anorexia weigh less than 85% of the normal weight for their age and
height. Excessive exercise, vomiting, and abuse of laxatives and/or diuretics may also occur. Severe anorexia can be life
threatening.
Bulimia, also known as bingeing and purging, is more common than anorexia, and usually
affects teenage girls and women in their twenties. It involves a recurring, emotionally driven
cycle of compulsive consumption of large quantities of high-calorie food in a short period of
time, followed by induced vomiting. Some individuals also use laxatives, drugs that induce
vomiting, diuretics, or excessive exercise in an attempt to purge. About 50% of anorexics also
purge, and both bulimia and anorexia can coexist in the same person.2 Unlike those
with anorexia, some people affected by bulimia maintain normal or even excessive body
weight.
Binge-eating disorder is similar to bulimia but no purging is done. It is more common than
either bulimia or anorexia nervosa, and people with binge-eating disorder are usually
overweight.3
What are the symptoms of eating disorders?
People with eating disorders may have a preoccupation with weight and food, anxiety about
their body image, and/or a feeling that they lose control over how much they eat. They may
also exercise compulsively and, in women, experience missed menstrual periods. They may also
frequently use laxatives, diet pills, and medicines designed to induce vomiting or reduce
fluid retention.
Medical treatments for eating disorders
Prescription medications commonly prescribed for bulimia include the selective serotonin
reuptake inhibitors fluoxetine (Prozac®),
paroxetine (Paxil®), sertraline (Zoloft®), venlafaxine (Effexor®), and fluvoxamine (Luvox®), as well as the tricyclic antidepressants amitriptyline
(Elavil®), desipramine (Norpramin®), and imipramine (Tofranil®). Individuals
with anorexia nervosa are sometimes prescribed the antihistamine cyproheptadine (Periactin®) to stimulate
appetite.
Treatment for eating disorders also includes psychological counseling, such as
cognitive-behavioral, interpersonal, psychodynamic, and family therapy.
Dietary changes that may be helpful for eating disorders
The most important dietary change for people with eating disorders is to eat a sufficient
amount of calories without purging. To accomplish this, most will need psychological as well
as nutrition counseling.
Individuals with both bulimia and anorexia are likely to report a craving for sugar; people
with bulimia eat more sweets and carbohydrates, particularly during binges, than do healthy
individuals.4 5 6 7 In a double-blind study,
bulimic subjects were reported to have significantly more mood changes after receiving glucose
(corn sugar) injections compared to placebo injections.8 Preliminary evidence
suggests that purging results in low blood sugar, which might increase the incidence of
repeated bingeing and purging by stimulating appetite or altering mood.9
In a preliminary trial, researchers fed ten bulimic women a diet free of all alcohol, caffeine, refined sugar, and foods containing
white flour, added salt, monosodium glutamate, and flavor enhancers. They were also given 1
gram of vitamin C, 50 mg of a vitamin B-complex, and a multiple vitamin and mineral supplement.10
Cigarette smoking was not allowed during the trial. After three weeks, all women on this diet
plan stopped bingeing whereas another ten bulimic women consuming a normal diet continued to
binge. When the women who had been eating a normal diet were also placed on the more healthful
diet plan, they too stopped bingeing. All 20 women remained binge-free for more than two and a
half years.
Lifestyle changes that may be helpful for eating disorders
Although regular, moderate exercise offers important health benefits, for many people
excessive exercise is a common component of eating disorders, especially anorexia
nervosa.11 In one controlled trial, a majority of the people with eating disorders
reported that participation in competitive sports and exercise performed as part of a weight
loss plan contributed to their condition.12 For people with eating disorders, it is
important to establish and maintain healthy exercise habits; these individuals should consult
with a healthcare professional skilled in eating disorders.
Nutritional supplements that may be helpful for eating disorders
People with eating disorders who restrict their food intake are at risk for multiple
nutrient deficiencies, including protein,
calcium, iron, riboflavin, niacin,13 folic acid,14 vitamin A, vitamin C,15 and vitamin B6,16 and essential fatty
acids.17 A general
multivitamin-mineral formula can reduce the detrimental health effects of these
deficiencies.
In a preliminary study of women with anorexia nervosa, those who supplemented with 45 mg of
vitamin K2 per day for approximately one year
experienced significantly less bone loss, compared with women who did not take the
supplement.18 This study suggests that supplementing with vitamin K2 may help
prevent osteoporosis, which is a common
complication of anorexia nervosa. The amount of vitamin K2 used in this study was much larger
than the amount of vitamin K found in food and most supplements. Moreover, vitamin K2 is not
yet generally available as a supplement, although it can be obtained through some
nutritionally oriented doctors. Individuals interested in using this treatment should be
monitored by a doctor.
Zinc deficiency has also been detected in
people with anorexia or bulimia in most,19 20 though not
all,21 studies. In addition, some of the manifestations of zinc deficiency, such as
reduced appetite, taste, and smell, are similar to symptoms observed in some cases of anorexia
or bulimia.22
In an uncontrolled trial, supplementation with 45–90 mg per day of zinc resulted in
weight gain in 17 out of 20 anorexics after 8–56 months.23 In a double-blind
study, 35 women hospitalized with anorexia, given 14 mg of zinc per day, achieved a 10%
increase in weight twice as fast as the group that received a placebo.24 In another
report, a group of adolescent girls with anorexia, some of whom were hospitalized, was found
to be consuming 7.7 mg of zinc per day in their diet—only half the recommended
amount.25 Providing these girls with 50 mg of zinc per day in a double-blind trial
helped diminish their depression and anxiety levels, but had no significant effect on
weight gain. Anyone taking zinc supplements for more than a few weeks should also supplement
with 1 to 3 mg per day of copper to prevent a
zinc-induced copper deficiency.
Serotonin, a hormone that helps regulate food intake and appetite, is synthesized in the
brain from the amino acid L-tryptophan.
Preliminary data suggest that some people with bulimia have low serotonin levels.26
Researchers have reported that bulimic women with experimentally induced tryptophan deficiency
tend to eat more and become more irritable compared to healthy women fed the same
diet,27 28 though not all studies have demonstrated these
effects.29
Weight-loss diets result in lower L-tryptophan and serotonin levels in women,30
which could theor
Holistic approaches that may be helpful for eating disorders
Psychological counseling, for both the individual and her family, and behavior modification
training are also commonly used for people with eating disorders, often as part of a team
approach that also includes nutrition counseling and medical care. Numerous preliminary and
controlled studies have shown that the psychotherapy technique known as cognitive-behavioral
therapy is effective in reducing the symptoms of bulimia.37 38 For
example, one study found 69% of a group receiving cognitive-behavioral therapy were abstaining
from binge-eating and purging six months later compared to only 15% of a group keeping a diary
of their behavior.39 Preliminary studies40 and one controlled
trial41 suggest another technique, interpersonal psychotherapy, is equally
effective for people with bulimia. Cognitive behavioral therapy and interpersonal
psychotherapy have also been effective for people with binge-eating disorder in controlled
trials,42 43 resulting in cessation of binge-eating in almost half of
the subjects in one report.44
The effectiveness of psychotherapy for anorexia nervosa is less clear.45
46 One controlled trial found that psychotherapy (type unspecified) significantly
improved weight gain compared to no treatment, and complete or nearly complete recovery
occurred in 60% of the patients.47 Two other studies comparing different types of
psychotherapy for anorexia nervosa found comparable improvement from all types;48
49 one of these studies reported moderate improvement in 63% of cases.50
Long-term effectiveness of psychotherapy for eating disorders has not been studied.
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The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in
vitro), clinical experience, or traditional usage as cited in each article.
The results reported may not necessarily occur in all individuals. For many of
the conditions discussed, treatment with prescription or over the counter
medication is also available. Consult your doctor, practitioner, and/or
pharmacist for any health problem and before using any supplements or before
making any changes in prescribed medications.
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